Several roadmaps are now pointing to the first undeniable demonstration of useful quantum advantage in 2024. We expect this demonstration to be in computational chemistry, on a use case relevant to pharma or materials engineering, which is why we have made investments in companies like QSimulate and Kvantify. This will be a turning point for the sector, and we expect it to generate an in-flux of funding, especially into companies developing the application layer for quantum computing, with established customer relationships. The integration of AI with quantum computing, which has started in earnest in 2023, will also continue to grow, and we will see quantum techniques increasingly being used to improve current generative models.